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New Books
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Toxicity and Risk: Context, Principles and Practice
Added 2/1/2008
H Paul A Illing Humans are constantly, and increasingly, exposed to chemicals - some naturally occurring and some manufactured. Exposure to some of these chemicals, or to large amounts of them, can bring risks to human health and the environment.
· How do we decide what is an acceptable level of risk? · Who is best-placed to make these assessments? · How are these assessments to be carried out?
Toxicity and Risk sets out the political, social, legal and scientific basis of risk assessment and risk management. Taking a highly multidisciplinary approach, the book discusses concepts of importance to industry, academia, health and safety bodies and society in general, such as individual risk and social risk. The role of government and the judicial system, and the contrast between EU, UK and US legal and administrative frameworks for handling risk analysis are also discussed.
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Regulatory Toxicology
Added 3/14/2008
Shayne Gad This practical resource provides toxicologists and scientists with essential information on the regulations that govern their jobs and products. Regulatory Toxicology also covers the scientific and historical underpinnings of those regulations. Each chapter provides a grounding in the historical events that led to the development of original legislation and major subsequent changes in legislation. The major administrative divisions for regulatory agencies and their main missions and responsibilities are also detailed, as are the basic filing units or documents the agencies require of individuals to meet goals. This second edition is updated to reflect new developments in the field.
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Site-Selective Neurotoxicity
Added 3/14/2008
David Lester, William SlikkerJr, Philip Lazarovici This unique volume provides interdisciplinary coverage of the mechanistic perspective of neurotoxicity that focuses on the site of action of known neurotoxins. It provides the reader with an insight into the common characteristics of neurotoxin action on the nervous system and examines sites of action at three levels of complexity: molecular, cellular, and brain, which will allow the development of more specific therapeutic and pharmacological rationales for treatment in the future. Site-Selective Neurotoxicity contains useful information for graduate students and academic and industrial researchers in the fields of toxicology, pharmacology, neurosciences and medicine.
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Antidotes: Principles and Clinical Applications
Added 3/14/2008
Robert Flanagan, Alison Jones, Robert Maynard Antidotes provides up-to-date information on the development and clinical use of antidotes, their proposed mechanism of action, toxicity, availability and practical aspects of their clinical use. The antidotes discussed are primarily those either in current use, or under consideration or development. Some other compounds of mainly historical interest are also mentioned where appropriate. It contains information on the antidotal treatment of poisoning with compounds encountered not only in Western Europe, North America and Australia, but also developing countries. It covers source, shelf-life and instances where antidote administration complicates or compromises laboratory analyses.
There is no other single, published work that looks generally at antidotes, and it will prove invaluable to researchers, staff in poison information centers and A&E wards, drug information pharmacists, medical toxicologists and veterinarians. It will also be useful reading for medical students, trainee pharmacists, emergency physicians, ambulance staff and anesthetists.
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Toxicological Risk Assessment of Chemicals: A Practical Guide
Added 3/28/2008
Elsa Nielsen, Grete Ostergaard, John Christian Larsen Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk assessment of chemical substances. It illustrates each step in the process: hazard identification, a dose response assessment, and exposure assessment. The book also summarizes the basic concepts of interaction of chemicals in mixtures and discusses various approaches to testing such mixtures.
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